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Bioinformatics Basics: Applications in Biological Science and Medicine



Bioinformatics Basics: Applications in Biological Science and Medicine

Bioinformatics Basics Applications in Biological Science and Medicine
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Bioinformatics Basics: Applications in Biological Science and Medicine

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Book Description
Scientists in the throes of research use an extensive data bank to access structural information on proteins and nucleic acids. Meanwhile, geneticists use a highly specialized form of software to analyze the hybridization pattern of DNA chips.The past decade has been tremendously successful for biotechnology and pharmaceutical industries. This success has been a result of astounding technical advancements in genome sequencing (genomics), protein identification (proteomics), and data analysis-collectively called bioinformatics. The exponential increase in computer processing and disk storage has served as a catalyst and been instrumental in the development of bioinformatics.Bioinformatics Basics: Applications in Biological Science and Medicine describes the origin of this field and the organization of public domain databases with an introductory tutorial for the services described. This book explains these services in a relatively simple fashion. Nevertheless, a biological background is necessary to understand and properly utilize the various software components and services described in this book. A basic biological background is also necessary for understanding the biological and medical significance of the collected data.Bioinformatics Basics is a fast growing field, and it will take some years for a stabilization to occur. Until then, hundreds of Internet sites allow us to search, compare, and manipulate this data in its relatively raw format. Bioinformatics Basics: Applications in Biological Science and Medicine concentrates on three major database clusters and relevant software tools that are maintained in the United States, Europe, and Japan, offering free access and analysis through the Internet.

Bioinformatics Basics: Applications in Biological Science and Medicine

Cell Biology-A Short Course



Cell Biology-A Short Course

Cell Biology-A Short Course

Cell Biology-A Short Course
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Book Description
This text tells the story of cells as the unit of life in a colorful and student-friendly manner, taking an “essentials only” approach. By using the successful model of previously published Short Courses, this text succeeds in conveying the key points without overburdening readers with secondary information.
The authors (all active researchers and educators) skillfully present concepts by illustrating them with clear diagrams and examples from current research. Special boxed sections focus on the importance of cell biology in medicine and industry today. This text is a completely revised, reorganized, and enhanced revision of From Genes to Cells.

Cell Biology-A Short Course

Bacteria in Biology, Biotechnology and Medicine By Paul Singleto



Bacteria in Biology, Biotechnology and Medicine By Paul Singleton

Bacteria in Biology, Biotechnology and Medicine By Paul Singleton
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Bacteria in Biology, Biotechnology and Medicine By Paul Singleton

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Book Description
Bacteria in Biology, Biotechnology and Medicine is a broadly based textbook of pure and applied bacteriology. Written in clear language, the up-to-date text gives readers access to new ideas and developments in the current literature. The book is intended primarily for undergraduates and postgraduates in biology, biotechnology, medicine, veterinary science, pharmacology, microbiology, food science, environmental science and agriculture; no prior knowledge of bacteria is assumed.
The sixth edition has been extensively updated; much of the text is new, or re-written, and there are many new references. Over 70 genera of bacteria, listed alphabetically, are described in the Appendix. Cross-references and a detailed index, maximise…
Reviews of previous editions:
“….a useful survey of the subject for students contemplating specialization.” —Nature
“Singleton assumes the reader has no prior knowledge of DNA and gene expression, and does an extraordinary job of explaining things from scratch.” —Quarterly Review of Biology
“….recommended to undergraduates and those seeking clear explanations of basic concepts of bacteriology.” —Journal of Medical Microbiology

Bacteria in Biology, Biotechnology and Medicine By Paul Singleton

Molecular Biotechnology: Principles and Applications of Recombinant DN



Molecular Biotechnology: Principles and Applications of Recombinant DNA

Molecular Biotechnology: Principles and Applications of Recombinant DNA
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Molecular Biotechnology: Principles and Applications of Recombinant DNA

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Book Description
Molecular biotechnology emerged as a new research field that arose as a result of the fusion in the late 1970s of recombinant DNA technology and traditional industrial microbiology. Whether one goes to the movies to see Jurassic Park with its ingenious but scientifically untenable plot of cloning dinosaurs, reads in the newspaper about the commercialization of a new “biotech” tomato that has an extended shelf life, or hears one of the critics of molecular biotechnology talking about the possibility of dire consequences from genetic engineering, there is a significant public awareness about recombinant DNA technology. In this book, we introduce and explain what molecular biotechnology actually is as a scientific discipline, how the research in the area is conducted, and how this technology may realistically impact on our lives in the future. We have written Molecular Biotechnology: Principles and Applications of Recombinant DNA to serve as a text for courses in biotechnology, recombinant DNA technology, and genetic engineering or for any course introducing both the principles and the applications of contemporary molecular biology methods. The book is based on the biotechnology course we have offered for the past 12 years to advanced undergraduate and graduate students from the biological and engineering sciences at the University of Waterloo. We have written this text for students who have an understanding of basic ideas from biochemistry, molecular genetics, and microbiology. We are aware that it is unlikely that students will have had all of these courses before taking a course on biotechnology. Thus, we have tried to develop the topics in this text by explaining their broader biological context before delving into molecular details. This text emphasizes how recombinant DNA technology can be used to create various useful products. We have, wherever possible, used experimental results and actual methodological strategies to illustrate basic concepts, and we have tried to capture the flavor and feel of how molecular biotechnology operates as a scientific venture. The examples that we have selected—from a vast and rapidly growing literature—were chosen as case studies that not only illustrate particular points but also provide the reader with a solid basis for understanding current research in specialized areas of molecular biotechnology. Nevertheless, we expect that some of our examples will be out of date by the time the book is published, because molecular biotechnology is such a rapidly changing discipline.
For the ease of the day-to-day practitioners, scientific disciplines often develop specialized terms and nomenclature. We have tried to minimize the use of technical jargon and, in many instances, have deliberately used a simple phrase to describe a phenomenon or process that might otherwise have been expressed more succinctly with technical jargon. In any field of study, synonymous terms that describe the same phenomenon exist. In molecular biotechnology, for example, recombinant DNA technology, gene cloning, and genetic engineering, in a broad sense, have the same meaning. When an important term or concept appears for the first time in this text, it is followed in parentheses with a synonym or equivalent expression. An extensive glossary can be found at the end of the book to help the reader with the terminology of molecular biotechnology.

Molecular Biotechnology: Principles and Applications of Recombinant DNA

Molecular Biology and Biotechnology By John M. Walker, Ralph Rapley



Molecular Biology and Biotechnology By John M. Walker, Ralph Rapley

Molecular Biology and Biotechnology By John M. Walker, Ralph Rapley
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Molecular Biology and Biotechnology By John M. Walker, Ralph Rapley

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Book Description


This popular textbook has been completely revised and updated to provide a comprehensive overview and to reflect all the latest developments in this rapidly expanding area. Chapters on the impact of molecular biology in the development of biotechnology have been fully updated and include the applications of molecular biology in the areas of drug design and diseases. There are also completely new chapters in developing areas such as genome technology, nanobiotechnology, regenerative medicine and biofuels. By presenting information in an easily assimilated form, this book makes an ideal undergraduate text.
From the Back Cover
One of the exciting aspects of being involved in the field of molecular biology is the ever-accelerating rate of progress, both in the development of new methodologies and the practical applications of these methodologies. This popular textbook has been completely revised and updated to provide a comprehensive overview and to reflect all the latest developments in this rapidly expanding area. Chapters on the impact of molecular biology in the development of biotechnology have been fully updated and include the applications of molecular biology in the areas of drug design and diseases. The first six chapters deal with the technology used in current molecular biology and biotechnology. These primarily deal with core nucleic acid techniques and protein expression through microbial and genetic detection methods. Further chapters address the huge advances made in gene and genome analysis and updates the rapid advances into yeast analysis, which is providing very exciting insights into molecular pathways. There are also completely new chapters in developing areas such as genome technology, nanobiotechnology, regenerative medicine and biofuels. In addition, the authors continue to ensure that biotechnology is not just considered at the gene level and full consideration continues to be given to applications and manufacturing, with chapters on downstream processing, biosensors, the applications of immobilised biocatalysts, and a new chapter on the developing area of biofuels. By presenting information in an easily assimilated form, this book makes an ideal undergraduate text. Molecular Biology and Biotechnology 5th Edition will be of particular interest to students of biology and chemistry, as well as to postgraduates and other scientific workers who need a sound introduction to this ever rapidly advancing and expanding area.

Molecular Biology and Biotechnology By John M. Walker, Ralph Rapley

Bacteria in Biology, Biotechnology and Medicine By Paul Singleton




Bacteria in Biology, Biotechnology and Medicine By Paul Singleton

Bacteria in Biology, Biotechnology and Medicine By Paul Singleton
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Bacteria in Biology, Biotechnology and Medicine By Paul Singleton

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Book Description
Bacteria in Biology, Biotechnology and Medicine is a broadly based textbook of pure and applied bacteriology. Written in clear language, the up-to-date text gives readers access to new ideas and developments in the current literature. The book is intended primarily for undergraduates and postgraduates in biology, biotechnology, medicine, veterinary science, pharmacology, microbiology, food science, environmental science and agriculture; no prior knowledge of bacteria is assumed.
The sixth edition has been extensively updated; much of the text is new, or re-written, and there are many new references. Over 70 genera of bacteria, listed alphabetically, are described in the Appendix. Cross-references and a detailed index, maximise…
Reviews of previous editions:
“….a useful survey of the subject for students contemplating specialization.” —Nature
“Singleton assumes the reader has no prior knowledge of DNA and gene expression, and does an extraordinary job of explaining things from scratch.” —Quarterly Review of Biology
“….recommended to undergraduates and those seeking clear explanations of basic concepts of bacteriology.” —Journal of Medical Microbiology

Bacteria in Biology, Biotechnology and Medicine By Paul Singleton

Fruit and Vegetable Biotechnology By Victoriano Valpuesta


Fruit and Vegetable Biotechnology By Victoriano Valpuesta

Fruit and Vegetable Biotechnology By Victoriano Valpuesta
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Fruit and Vegetable Biotechnology By Victoriano Valpuesta

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Book Description
Genetic modification is one of the most important and controversial issues facing the food industry today. Drawing on an international team of contributors, Fruit and Vegetable Biotechnology explores its major impact on fruit and vegetable cultivation and subsequent food processing.The book begins with an analysis of the available tools and methods, from the selection and isolation of genes to safety issues such as the stability of transgenes. The contributors discuss the range of properties that have been the subject of genetic enhancement, including agronomic traits such as fruit quality and resistance to environmental stresses, as well as sensory properties such as color, flavor, processing functionality, and nutritional quality. In addition, the text also examines the use of molecular markers in plant breeding. The subsequent chapters consider how biotechnology can improve plant defense mechanisms and also extend the post-harvest life of fruit and vegetables.Thorough case studies illustrate the efforts involved and the positive effects resulting from genetic modification, and also offer insight into future applications. To complete their survey of this field, the authors explore the vital issues of consumer attitudes and risk assessment. Fruit and Vegetable Biotechnology is an important contribution to a key area of debate, and is essential reading for everyone involved in the cultivation and processing of fruit and vegetables.

Fruit and Vegetable Biotechnology By Victoriano Valpuesta

Handbook on Cyanobacteria: Biochemistry, Biotechnology and Applications



Handbook on Cyanobacteria: Biochemistry, Biotechnology and Applications

Handbook-on-Cyanobacteria-Biochemistry,-Biotechnology-and-Applications
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Handbook on Cyanobacteria: Biochemistry, Biotechnology and Applications

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Books Description
Cyanobacteria, also known as blue-green algae, blue-green bacteria or cyanophyta, is a phylum of bacteria that obtain their energy through photosynthesis. They are a significant component of the marine nitrogen cycle and an important primary producer in many areas of the ocean, but are also found in habitats other than the marine environment; in particular, cyanobacteria are known to occur in both freshwater and hypersaline inland lakes. They are found in almost every conceivable environment, from oceans to fresh water to bare rock to soil.
Cyanobacteria are the only group of organisms that are able to reduce nitrogen and carbon in aerobic conditions, a fact that may be responsible for their evolutionary and ecological success. Certain cyanobacteria also produce cyanotoxins. This new book presents a broad variety of international research on this important organism.

Handbook on Cyanobacteria: Biochemistry, Biotechnology and Applications

Biofertilizer Manual By FNCA



Biofertilizer Manual By FNCA

Biofertilizer-Manual1
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Biofertilizer Manual By FNCA

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Books Description
The biofertilizer manual published March 2006 is the product of the Biofertilizer Project in FNCA (Forum for Nuclear Cooperation in Asia). Eight countries, China, Indonesia, Japan, Korea, Malaysia, Philippines, Thailand, and Viet Nam participate in this project. The Editor-in-Chief is Dr. Pham Van Toan, the Project Leader of Viet Nam. The manual is written by project members and other experts to share information and experiences of biofertilizer use in Asian countries, their effectiveness, efficient production processes, storage and application on different crops.
The manual has the following chapters:
1) Introduction,
2) General methods to evaluate microbial activity,
3) Carriers for biofertilizers,
4) Inoculant for biofertilizers including rhizobia, non-symbiotic nitrogen fixers, mycorrhiza, phosphorous solubilizers, and
5) Quality control of biofertilizers, from advanced basic information to practical methods in each participating country.
The manual was written as easy as possible for scientists and technicians involved in biofertilizersin Asia. However, the manual may be quite difficult for farmers. It is our hope that scientists and technicians will translate some part of the manual into the respective mother language in some brochures or pamphlets for farmers.
The manual is able to be downloaded from this website. It is desired that this manual would be useful for improving and disseminating biofertilizer technology, and enhancing environmental friendly sustainable farming practices by reducing excessive amount of chemical fertilizer application.

Biofertilizer Manual By FNCA

Basic Laboratory Procedures in Clinical Bacteriology



Basic Laboratory Procedures in Clinical Bacteriology

Basic Laboratory Procedures in Clinical Bacteriology
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Basic Laboratory Procedures in Clinical Bacteriology

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Books Description
Communicable diseases are the most common cause of death in developing countries, and their diagnosis and treatment represent a significant challenge to the health services in those areas. The World Health Organization has long
been actively involved in developing and promoting standard techniques for laboratory investigations of such diseases, a first attempt to standardize susceptibility testing of bacterial pathogens being made in 1960. Following on from this, in 1976, the WHO Expert Committee on Biological Standardization drew up requirements for antibiotic susceptibility testing using the disc method.
At the same time, efforts were being made to introduce quality control into laboratory performance. In 1981, WHO established an International External Quality Assessment Scheme for Microbiology. The laboratories that are involved in this scheme are able to play a leading role in the implementation of national quality assessment schemes at all levels of the health care system.
The present publication brings together and updates the various guidelines produced by WHO over the years on sampling of specimens for laboratory investigation, identification of bacteria, and testing of antimicrobial resistance. The information included is intended to lead to harmonization of microbiological investigations and susceptibility testing, and to improve the quality of laboratories at both central and intermediate levels. It concentrates on the procedures to be followed, rather than the basic techniques of microscopy and staining, which have been described in detail in another WHO publication

Basic Laboratory Procedures in Clinical Bacteriology

Clinical Microbiology Made Ridiculously Simple



Clinical Microbiology Made Ridiculously Simple

Clinical Microbiology Made Ridiculously Simple
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Clinical Microbiology Made Ridiculously Simple

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A brief, clear, thorough, and highly enjoyable approach to clinical microbiology, brimming with mnemonics, humor, summary charts and illustrations, from AIDS to “flesh-eating bacteria” to ebola, mad cow disease, hantavirus, anthrax, smallpox, botulism, etc. New chapter on hospital-acquired infections.
TABLE OF CONTENTS
PART 1. BACTERIA
1. Bacterial Taxonomy
2. Cell Structures, Virulence Factors, and Toxins
3. Bacterial Genetics (Sex)
GRAM-POSITIVE BACTERIA
4. Streptococcus
5. Staphylococcus
6. Bacillus and Clostridium (Spore-Forming Rods)
7. Corynebacterium and Listeria (Non-Spore-Forming Rods)
GRAM-NEGATIVE BACTERIA
8. Neisseria
9. The Enterics
10. Hospital-Acquired Gram Negatives
11. Haemophilus, Bordetella, and Legionella
12. Yersinia, Francisella, Brucella, and Pasteurella
13. Chlamydia, Rickettsia, and Friends
14. Spirochetes
ACID-FAST BACTERIA
15. Mycobacterium
BACTERIA WITHOUT CELL WALLS
16. Mycoplasma
ANTI-BACTERIAL MEDICATIONS
17. Penicillin Family Antibiotics
18. Anti-ribosomal Antibiotics
19. Anti-Tb and Anti-leprosy Antibiotics
20. Miscellaneous Antibiotics
PART 2. FUNGI
21. The Fungi
22. Anti-fungal Medications
PART 3. VIRUSES
23. Viral Replication and Taxonomy
24. Orthomyxo and Paramyxoviridae
25. Hepatitis Viridae
26. Retroviridae, HIV, and AIDS
27. Herpseviridae
28. Rest of the DNA Viruses
29. Rest of the RNA Viruses
30. Anti-viral Medications
PART 4. PARASITES
31. Protozoans
32. Helminths
PART 5. VERY STRANGE CRITTERS
33. Prions
PART 6. THE END
34. Antimicrobial Resistance: One Step Toward the Post-antibiotic Era
35. The Agents of Bioterrorism
About the Author
Dr. Gladwin is Division Chief, Pulmonary, Allergy and Critical Care Medicine at the University of Pittsburgh Medical Center, and Director, Vascular Medicine Institute of the University of Pittsburgh.
Dr. Trattler is in private practice.

Clinical Microbiology Made Ridiculously Simple

CLSI M100-S23 Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Third Informational Supplement 2013



CLSI M100-S23 Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Third Informational Supplement 2013

CLSI Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Third Informational Supplement 2013
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CLSI M100-S23 Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Third Informational Supplement 2013

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Book Description
M100-S23 includes a dosage regimen for imipenem for Pseudomonas aeruginosa and new information for detection of inducible clindamycin resistance using the D-zone test or broth microdilution for Streptococcus pneumoniae. Also, the disk diffusion and minimal inhibitory concentration quality control frequency has been updated to include a new two-phase, 15-replicate (3 × 5 day) plan and flow chart. Expanded recommendations for testing fluoroquinolones and salmonella, and elimination breakpoints for beta-lactamase, other than oxacillin (cefoxitin), penicillin, and ceftaroline for staphylococci are included.
Jean B. Patel, PhD, D(ABMM), Deputy Director of the Office of Antimicrobial Resistance for the Centers for Disease Control and Prevention in Atlanta, Georgia, USA, and Vice-Chairholder of the CLSI Subcommittee on Antimicrobial Testing Standards, stated that, “There are a number of changes in this latest version of M100, but perhaps the most significant are the new ceftaroline interpretive criteria (or breakpoints) for several bacterial genera including Staphylococcus aureus, the new doxycycline, revised tetracycline breakpoints for Streptococcus pneumoniae, and the simplified Staphylococcus spp. table.”
This January, instantly access M100-S23 with CLSI’s new electronic product. eM100 is an interactive, searchable database for drug selection, interpretation, and QC procedures. Work more efficiently by providing the latest recommendations for detecting emerging resistance in an easy-to-use format. There is a version specifically designed for pharmacists to enhance the implementation of M100 information tailored to their organization.
The Clinical and Laboratory Standards Institute (CLSI) is a not-for-profit membership organization that brings together the varied perspectives and expertise of the worldwide laboratory community for the advancement of a common cause: to foster excellence in laboratory medicine by developing and implementing clinical laboratory standards and guidelines that help laboratories fulfill their responsibilities with efficiency, effectiveness, and global applicability. For additional information, visit the CLSI website at www.clsi.org or call 610.688.0100.

CLSI M100-S23 Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Third Informational Supplement 2013

Cell Biology, Genetics, Molecular Biology, Evolution and Ecology by Verma, Agarwal



Cell Biology, Genetics, Molecular Biology, Evolution and Ecology by Verma, Agarwal

Cell Biology, Genetics, Molecular Biology, Evolution and Ecology by Verma, Agarwal
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Cell Biology, Genetics, Molecular Biology, Evolution and Ecology by Verma, Agarwal

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Book Description
The multicoloured edition of the textbook of Cell Biology, Genetics, Molecular Biology, Evolution and Ecology is the outcome of sincere and combined efforts of the authors and editors (namely Shishir Bhatnagar, Shubha Pradhan, Malini Kothiyal) and young but talented persons of DTP of S.Chand & Company Ltd. Their main motive remained to provide relevant coloured photographs explaining various intricate biological
topics. Multicoloured figures and photographs of this edition would help our target readers to understand and fully appreciate the very gist of the subject matter. Authors and editors have remained quite choosy and vigilant regarding relevance and authenticity of each and every illustration/picture finding its place in this textbook.
Authors earnestly hope that this multicoloured edition of the textbook of Cell Biology, Genetics, Molecular Biology, Evolution and Ecology will enhance the curiosity of our target readers to know more and more about the subject. It will arm them with latest information for facing any type of exam quite adequately.
This book is meant for students of B.Sc., B.Sc. (Hons.) and M.Sc. of biological group. Students appearing in entrance exams of C.P.M.T., I.F.S., P.C.S. and I.A.S., etc, may be immensely benefited by this book.

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